May 15, 2021

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Britain launches trial of re-exposure to the virus for recovered patients


British scientists launched a new “human challenge test” on the 19th, which will deliberately expose subjects who have been infected with covid-19 to the virus again to observe the immune response and whether they will be infected again.

According to Xinhua, the lead researcher of the challenge trial and Oxford University vaccinologist McShane said that the information provided by the trial “allows us to develop better vaccines and therapies, and to understand whether people are protected and protected after being infected with coronary disease.” How long does the force last”. McShane believes that the test also helps to understand what kind of immune response can prevent reinfection.

The first phase of the trial will determine the minimum amount of virus needed to allow the virus to start replicating in about 50% of volunteers and cause mild or even asymptomatic symptoms. The second phase of the experiment was launched in the summer, and different volunteers will be infected with the standard virus dose. A total of 64 volunteers in the first phase, ranging in age from 18 to 30, are in good health and have contracted coronary disease at least three months ago. The researchers let the volunteers be infected again with the original SARS-CoV-2 strain, and then let them quarantine for at least 17 days and observe them. Once symptoms appear, volunteers will receive monoclonal antibody treatment.

According to a report by Deutsche Welle, voluntary subjects will be exposed to the virus in a “safe and monitored environment” accompanied by a team of experts. Volunteers tested will each receive nearly 5,000 pounds in compensation.

In February, the United Kingdom became the first country in the world to approve a “human challenge test” for covid-19. Volunteers were exposed to coronavirus to conduct research on the pathogenicity of coronavirus.

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